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Saturday, 15 October 2016

Potential Antioxidant and Antidiabetic Activities of Kayu Kuning (Arcangelisia Flava) ☆

Published Date
doi:10.1016/j.aaspro.2016.02.155
International Conference on Food, Agriculture and Natural Resources, IC-FANRes 2015
Open Access, Creative Commons license


  • Author 

  • Duwi Wahyudi a
  • Anak Agung Istri Ratnadewi a
  • Tri Agus Siswoyo b,c,,
    • aDepartment of Chemistry, Faculty of Mathematic and Natural Sciences, Jember University, Kampus Tegal Boto Jl. Kalimantan 37, Jember, East Java 68121, Indonesia
    • bCenter for Development of Advanced Sciences and Technology, Jember University, Kampus Tegal Boto Jl. Kalimantan 37, Jember, East Java 68121, Indonesia
    • cDepartment of Agronomy, Faculty of Agriculture, Jember University, Kampus Tegal Boto Jl. Kalimantan III/23, Jember, East Java 65121, Indonesia
    Available online 23 February 2016.

    Abstract

    Kayu kuning has already used as traditional medicine to treat various disease. The aim of this study was to evaluate the in vitro antioxidant and antidiabetic activity of hexane, ethyl acetate, and methanol extract of Kayu kuning leaves. The antioxidant activities of the Kayu kuning extracts were measured by 2, 2-diphenyl-1-picrylhydrazyl (DPPH), superoxide radical, and hydroxyl radical assays. The antidiabetic activity was evaluated by α-amylase and α-glucosidase inhibition assays. Compared with the standard vitamin C, extract hexane, ethyl acetate, and methanol of Kayu kuning shown potent as antioxidant. The methanol extract showed highest scavenging activity on superoxide and hydroxyl radical. The ethyl acetate extract showed highest scavenging activity on DPPH radical. Compared with the standard acarbose, extract hexane and ethyl acetate of Kayu kuning shown potent as antidiabetic while the methanol extract had no potent. The ethyl acetate extract showed highest potent as antidiabetic.

    Keywords

  • antidiabetic
  • antioxidant
  • Kayu kuning
  • scavenging activity

  • inhibition assay



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    • ☆
      Peer-review under responsibility of the organizing committee of IC-FANRes 2015.
    • ⁎ 
      Corresponding author. Tel.: +62 8179607263.

    For further details log on website :
    http://www.sciencedirect.com/science/article/pii/S2210784316301541
    Posted by A. Haikal at 9:07:00 am
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