The chemical composition and antioxidant activities of the essential oil from clove buds toward various oxidative stresses in vitro were investigated in this work. The results showed that 22 compositions of the essential oil were identi?ed by gas chromatography (GC) and GC-mass spectrometry (MS), and engenol (76.23%) was found to be the main components of the essential oil, followed by ß-caryophyllene (11.54%), caryophyllene oxide (4.29%), and eugenyl acetate (1.76%). The essential oil from clove buds had the better scavenging capacity against 2, 2’-azino-bis (3-ethylbenothiazoline-6-sulfonic acid) diammonium salts (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, high reducing power, and inhibiting lipid peroxidation reaction in lard emulsion, as well as exhibited different protection effects against DNA damage caused by Fe2+ and 2,2'-azobis (2-methylpropionamidine) dihydrochloride (AAPH). And the antioxidant activities of essential oil showed a dose-response relationship to some degree. However, the essential oil did not have the protection against protein damage, but had a prooxidant effect on protein oxidative damage.
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