Published Date
antioxidant
Kayu kuning
scavenging activity
inhibition assay
For further details log on website :
http://www.sciencedirect.com/science/article/pii/S2210784316301541
doi:10.1016/j.aaspro.2016.02.155
International Conference on Food, Agriculture and Natural Resources, IC-FANRes 2015
Open Access, Creative Commons license
Available online 23 February 2016.
Abstract
Kayu kuning has already used as traditional medicine to treat various disease. The aim of this study was to evaluate the in vitro antioxidant and antidiabetic activity of hexane, ethyl acetate, and methanol extract of Kayu kuning leaves. The antioxidant activities of the Kayu kuning extracts were measured by 2, 2-diphenyl-1-picrylhydrazyl (DPPH), superoxide radical, and hydroxyl radical assays. The antidiabetic activity was evaluated by α-amylase and α-glucosidase inhibition assays. Compared with the standard vitamin C, extract hexane, ethyl acetate, and methanol of Kayu kuning shown potent as antioxidant. The methanol extract showed highest scavenging activity on superoxide and hydroxyl radical. The ethyl acetate extract showed highest scavenging activity on DPPH radical. Compared with the standard acarbose, extract hexane and ethyl acetate of Kayu kuning shown potent as antidiabetic while the methanol extract had no potent. The ethyl acetate extract showed highest potent as antidiabetic.
Keywords
antidiabetic
Abstract
Kayu kuning has already used as traditional medicine to treat various disease. The aim of this study was to evaluate the in vitro antioxidant and antidiabetic activity of hexane, ethyl acetate, and methanol extract of Kayu kuning leaves. The antioxidant activities of the Kayu kuning extracts were measured by 2, 2-diphenyl-1-picrylhydrazyl (DPPH), superoxide radical, and hydroxyl radical assays. The antidiabetic activity was evaluated by α-amylase and α-glucosidase inhibition assays. Compared with the standard vitamin C, extract hexane, ethyl acetate, and methanol of Kayu kuning shown potent as antioxidant. The methanol extract showed highest scavenging activity on superoxide and hydroxyl radical. The ethyl acetate extract showed highest scavenging activity on DPPH radical. Compared with the standard acarbose, extract hexane and ethyl acetate of Kayu kuning shown potent as antidiabetic while the methanol extract had no potent. The ethyl acetate extract showed highest potent as antidiabetic.
Keywords
References
- International, 2003
- International Diabetes Federation., 2003. Diabetes Atlas. Second Edition. Belgium: Imprimerie L Vanmelle SA, Gent/Mariakerke.
- Wolff, 1993
- Diabetes mellitus and free radicals: Free Radicals
- Transition Metals and Oxidative Stress In The Aetiology of Diabetes Mellitus and Complications. British Medical Bulletin, Volume 49, Issue 3, 1993, pp. 432–642
- Guigliano et al., 1996
- Oxidatif Stress and Diabetic Vascular Complication
- Diabetes Care, Volume 19, Issue 3, 1996, pp. 257–267
- Maritim et al., 2003
- Diabetes Oxidative Stress, and Antioxidants: A Review. J Biochem Molecular Toxicology, Volume 17, Issue 1, 2003, pp. 24–37
- Sudha et al., 2011
- Anti hyperlipidemic activity of Spirulina platensisin Triton x-100 Induced Hyperlipidemic Rats
- Journal For Drugs and Medicines, Volume 3, Issue 2, 2011, pp. 32–37
- Nanheesha et al., 2007
- Study on Antioxidant Activity of Indian Gooseberry Fruit and Seed J
- Sci, Volume 3, 2007, pp. 83–92
- Subeki. et al., 2004
- Antibabasial Activity of Protoberberine Alkaloids and 20-Hydroxyecdysone from Arcangelisia flava against Babesia gibsoni in Culture
- J. Vet. Med. Sci, Volume 67, Issue 2, 2004, pp. 223–227
- Keawpradub et al., 2005
- Antioxidant and cytotoxic activities of Thai medicinal plants named Khaminkhruea: Arcangelisia flava
- Coscinium blumeanum and Fibraurea tinctoria. J. Sci. Technol, Volume 27, Issue 2, 2005, pp. 455–467
- Taga et al., 1984
- Chia seeds as a source of nature lipid antioxidants
- J. Am. Oil. Chem. Soc, Volume 61, 1984, pp. 928–931
- Chang et al., 2002
- Antioxidant activity and free radical scavenging capacity between Korean medicinal Plants and flavonoids by assay-guided comparison
- Plant Sci, Volume 163, 2002, pp. 1161–1168
- Wang et al., 2012
- TLC Screening for Antioxidant Activity of Extracts from Fifteen Bamboo Species and Identification of Antioxidant Flavone Glycosides from Leaves of Bambusa. textilis McClure
- Molecules, Volume 17, 2012, pp. 12297–12311
- |
- Soler-Rivas et al., 2000
- An easy and fast test to compare total free radical scavenger capacity of food stuffs
- Phytochem. Anal, Volume 11, 2000, pp. 330–338
- |
- Tang et al., 2010
- Peptide Fractionation and Free Radical Scavenging Activity of Zein Hydrolysate
- J. Agric. Food Chem, Volume 58, 2010, pp. 587–593
- |
- Halliwell et al., 1987
- The Deoxyribose Method: A Simple Test Tube Assay for The Determination of Rate Constants for Reactions of Hydroxyl Radicals
- Anal. Biochem, Volume 165, 1987, pp. 215–219
- | |
- Hashim et al., 2013
- Antioxidant and Alpha Amylase Inhibitory Property of Phyllanthus virgatus L.: An In Vitro and Molecular Interaction Study. BioMed Research International 2013
- Article ID 729393, 12 pages, doi:10.1155/2013/729393, 2013
- Miyazawa et al., 2005
- Inhibitory Compounds of α-Glucosidase Activity from Arctium lappa L
- J. Oleo Sci, Volume 54, Issue 11, 2005, pp. 589–594
- |
- ☆Peer-review under responsibility of the organizing committee of IC-FANRes 2015.
- ⁎ Corresponding author. Tel.: +62 8179607263.
For further details log on website :
http://www.sciencedirect.com/science/article/pii/S2210784316301541
No comments:
Post a Comment