Chitosan functionalized poly(vinyl alcohol) for prospects biomedical and industrial applications: A review

Published Date

June 2016, Vol.87:141–154, doi:10.1016/j.ijbiomac.2016.02.035

Review

Title 

Chitosan functionalized poly(vinyl alcohol) for prospects biomedical and industrial applications: A review

• Author 

• Ammara Rafique
• Khalid Mahmood Zia
• Mohammad Zuber ^,
• Shazia Tabasum
• Saima Rehman

• Institute of Chemistry, Government College University, Faisalabad, Pakistan

Received 6 January 2016. Revised 3 February 2016. Accepted 11 February 2016. Available online 15 February 2016.

Highlights

• •
  Human history mainly relies on the biopolymers.
• •
  Polyvinyl alcohol (PVA) has good mechanical, chemical and physical properties.
• •
  Functionalization of PVA with chitosan is appropriate for the development of chic biomaterials.
• •
  The review shed a light on chitosan based PVA materials with their potential applications.
• •
  Scientific issues have been addressed highlighting the recent advancement in the biomedical field.

Abstract

Chitin and chitosan are amino polysaccharides having multidimensional properties, such as biocompatibility, biodegradability, antibacterial properties and non-toxicity, muco-adhesivity, adsorption properties, etc., and thus they can be widely used in variety of areas. Although human history mainly relies on the biopolymers, however synthetic materials like polyvinyl alcohol (PVA) have good mechanical, chemical and physical properties. Functionalization of PVA with chitin and chitosan is considered very appropriate for the development of well-designed biomaterials such as biodegradable films, for membrane separation, for tissue engineering, for food packaging, for wound healing and dressing, hydro gels formation, gels formation, etc. Considering versatile properties of the chitin and chitosan, and wide industrial and biomedical applications of PVA, this review sheds a light on chitin and chitosan based PVA materials with their potential applications especially focusing the bio-medical field. All the technical scientific issues have been addressed highlighting the recent advancement.

Abbreviation

• AFS, applied field strength
• CS, Chitosan
• CH, Chitin
• DSC, Differential Scanning Calorimetry
• DMEM, Dulbecco’s modified Eagle’s medium
• FBS, fetal bovine serum
• FE-SEM, Field Emission Scanning Electron Microscopy
• FTIR, Fourier Transform Infrared Spectroscopy
• GTR, guided tissue regeneration membrane
• HPN, hybrid polymer network
• HRP, horseradish peroxidase
• PET, poly(ethylene terephtalate)
• PVA, poly vinyl alcohol
• PVC, poly vinyl chloride
• NMR, Nulear Magnetic Resonance Spectroscopy
• QCh, quaternized chitosan
• (n_e)_soln, solution entanglement number
• TEOS, tetraethylorthosilicate
• TS, tensile strength
• Tm, transition melting
• Tg, Glass Transition Temperature
• UV–Vis, ultra violet–visible
• WAC, Water absorption capacity
• XRD, X-ray diffraction

Keywords

• Chitosan
• Poly(vinyl alcohol)
• Biomedical applications
• Recent advances

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• ⁎ 
  Corresponding author. Fax: +92 41 9200764.
  
  

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