Constitutive Modeling of the Mechanical Response of Nanocomposite Hydrogels for Tissue Engineering

Published Date
Procedia Engineering

2013, Vol.59:37–45, doi:10.1016/j.proeng.2013.05.091

3rd International Conference on Tissue Engineering, ICTE2013

Open Access, Creative Commons license

Author 

• A.D. Drozdov ^a,,
 
• J. de C. Christiansen ^b

• aDanish Technological Institute, Gregersensvej 7, Taastrup 2630,Denmark
• bAalborg University, Fibigerstraede 16, Aalborg 9220, Denmark

Available online 5 June 2013. 

Abstract

A model is developed for the elastic behavior of nanocomposite hydrogels subjected to swelling-drying under an arbitrary deformation with finite strains. Novel constitutive equations are derived based on the Flory concept of flexible chains with constrained junctions and solvent-dependent reference configuration. Adjustable parameters in the stress-strain relations are found by fitting observations on N,N-dimethylacrylamide/hectorite nanoclay hydrogels. The constitutive model describes adequately the mechanical response of nanocomposite hydrogels subjected to swelling-drying and solvent exchange.

Keywords

• Nanocomposite hydrogel
• Finite elasticity
• Swelling
• Constitutive equations

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• ☆
  Selection and peer-review under responsibility of the Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, Centro Empresarial da Marinha Grande.

• ⁎ 
  Corresponding author. Tel.: +45 72 20 31 42; fax: +45 72 20 31 12.

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