Functional properties of dually modified sago starch/κ-carrageenan films: An alternative to gelatin in pharmaceutical capsules

Published Date
Carbohydrate Polymers
15 March 2017, Vol.160:43–51, doi:10.1016/j.carbpol.2016.12.042

• Author 

• Nazila Oladzadabbasabadi ^a
• Shokoufeh Ebadi ^b
• Abdorreza Mohammadi Nafchi ^c,,,
• A.A. Karim ^d
• Seyed Rahim Kiahosseini ^c

• aDepartment of Chemical Engineering, Shahrood Branch, Islamic Azad University, Shahrood, Iran
• bFood Science and Technology Department, Science and Research Branch, Islamic Azad University, Tehran, Iran
• cYoung Researchers and Elite Club, Damghan Branch, Islamic Azad University, Damghan, Iran
• dFood Biopolymer Research Group, Food Technology Division, School of Industrial Technology, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia

Received 28 November 2016. Revised 10 December 2016. Accepted 18 December 2016. Available online 20 December 2016. 

Highlights

• •
  A plant based alternative for gelatin in hard capsule industry.
• •
  A composite film based on dually modified sago starch and κ-carrageenan.
• •
  The composite film has similar properties to those of bovine gelatin film.
• •
  WVP of proposed system is significantly lower than gelatin.
• •
  The composite film was more stable at higher relative humidity than gelatin film

Abstract

The aim of this study was development a composite film based on sago starch and κ-carrageenan to find a gelatin alternative in the pharmaceutical capsules processing. Hydrolyzed-Hydroxypropylated (dually modified) sago starch was mixed with κ-carrageenan (0.25, 0.5, 0.75, and 1%). The drying kinetics, thermomechanical, physicochemical, and barrier properties of composite films were estimated and compared with bovine gelatin. Results show that drying kinetics and mechanical properties of the composite films were comparable to those of gelatin. The water vapor permeability and moisture content of the composite films were lower than those of gelatin. The solubility of the composite films was higher than that of gelatin, and the composite films were more stable at higher relative humidity than were the gelatin films. These results show that dually modified sago starch in combination with κ-carrageenan has properties similar to those of gelatin, thus proposed system can be used in pharmaceutical capsules processes.

Keywords

Dually modified starch

Bovine gelatin

Mechanical properties

Water vapor permeability

Drying kinetics

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• ⁎ 
  Corresponding author.
  
  

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