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E. Obeten Kebe, Patrick O. Ede, Victoria N. Isaac and Patricia P. Obasee
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International Journal of Medical and Health Sciences Research, 2015, vol. 2, issue 2, 25-35
Abstract: Zingerber offinale (ginger) is an underground stem or rhizome which is known to have originated from Asia and have been reported to have a number of medicinal properties which is used in the treatment of many ailments such as arthritis, painful menstrual periods, nausea etc. It is also used as a common specie in food and bakery industries. Due to the availability and medicinal uses of ginger, the effect of the ethanolic extract on the histology of the pancreas of adult wistar rats was investigated. Twenty five (25) adult Wistar rats weighing 125-200g were divided into five groups (A, B, C, D and E) each with five rats. The animals in group A and B served as control groups and received distilled water and olive oil respectively, the animals in groups C, D and E served as experimental groups, and received 100mg/kg, 250mg/kg and 500mg/kg body weight of the ethanolic extract of Zingiber officinale respectively. The animals received the extract for 14 days and were sacrificed 24 hours after the last administration and routinely processed histologically. The study shows that there is disintegration of the islet cells of Langerhans (IL) with pyknotic nuclei, but no visible change or alteration in the serous acini (SA) of the pancreas. It is observed that extract of ginger has adverse effect on the integrity of the islet cells of Langerhans.
Date: 2015
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International Journal of Medical and Health Sciences Research is currently edited by Sanele Phillip (Editorial Office)
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https://econpapers.repec.org/article/pkpijomah/2015_3ap_3a25-35.htm
E. Obeten Kebe, Patrick O. Ede, Victoria N. Isaac and Patricia P. Obasee
Additional contact information
International Journal of Medical and Health Sciences Research, 2015, vol. 2, issue 2, 25-35
Abstract: Zingerber offinale (ginger) is an underground stem or rhizome which is known to have originated from Asia and have been reported to have a number of medicinal properties which is used in the treatment of many ailments such as arthritis, painful menstrual periods, nausea etc. It is also used as a common specie in food and bakery industries. Due to the availability and medicinal uses of ginger, the effect of the ethanolic extract on the histology of the pancreas of adult wistar rats was investigated. Twenty five (25) adult Wistar rats weighing 125-200g were divided into five groups (A, B, C, D and E) each with five rats. The animals in group A and B served as control groups and received distilled water and olive oil respectively, the animals in groups C, D and E served as experimental groups, and received 100mg/kg, 250mg/kg and 500mg/kg body weight of the ethanolic extract of Zingiber officinale respectively. The animals received the extract for 14 days and were sacrificed 24 hours after the last administration and routinely processed histologically. The study shows that there is disintegration of the islet cells of Langerhans (IL) with pyknotic nuclei, but no visible change or alteration in the serous acini (SA) of the pancreas. It is observed that extract of ginger has adverse effect on the integrity of the islet cells of Langerhans.
Date: 2015
References: Add references at CitEc
Citations Track citations by RSS feed
Downloads: (external link)
http://www.conscientiabeam.com/journal/9/abstract/3391 (application/pdf)
http://www.conscientiabeam.com/journal/9/abstract/3391 (text/html)
Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.
Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text
Persistent link: https://EconPapers.repec.org/RePEc:pkp:ijomah:2015:p:25-35
Access Statistics for this article
International Journal of Medical and Health Sciences Research is currently edited by Sanele Phillip (Editorial Office)
More articles in International Journal of Medical and Health Sciences Research from Conscientia Beam 22 Sin Ming Lane #06-76 Midview City Singapore 573969.
Series data maintained by Editorial Office (info@conscientiabeam.com).
For further details logon website :
https://econpapers.repec.org/article/pkpijomah/2015_3ap_3a25-35.htm
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